• Western blot analysis of extracts of various cell lines, using PDE1A antibody (STJ112486) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-PDE1A antibody (446-545) (STJ112486)

SKU:
STJ112486

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDE1A (446-545) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PDE1A
Gene ID: 5136
Uniprot ID: PDE1A_HUMAN
Immunogen Region: 446-545
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 446-545 of human PDE1A (NP_005010.2).
Immunogen Sequence: EASKAETSSYVASSSTTIVG LHIADALRRSNTKGSMSDGS YSPDYSLAAVDLKSFKNNLV DIIQQNKERWKELAAQGESD LHKNSEDLVNAEEKHDETHS
Tissue Specificity Several tissues, including brain, kidney, testes and heart.
Function Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP.
Protein Name Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1a
Cam-Pde 1a
61 Kda Cam-Pde
Hcam-1
Database Links Reactome: R-HSA-111957
Reactome: R-HSA-418457
Reactome: R-HSA-418555
Alternative Antibody Names Anti-Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1a antibody
Anti-Cam-Pde 1a antibody
Anti-61 Kda Cam-Pde antibody
Anti-Hcam-1 antibody
Anti-PDE1A antibody

Information sourced from Uniprot.org

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