Anti-PDE10A antibody (1-50) {FITC} (STJ502207)

Name: Anti-PDE10A antibody (1-50) {FITC} (STJ502207)
SKU: STJ502207-100
Price: 686.55 USD
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationFITC

IsotypeIgG

ImmunogenSynthetic peptide taken within amino acid region 1-50 on human PDE10A2 protein.

STJ502207-100

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Short Description	Rabbit polyclonal antibody anti-PDE10A (1-50) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IP/WB
Host	Rabbit
Reactivity	Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	FITC
Concentration	0.75 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	PDE10A
Gene ID	10846
Uniprot ID	PDE10_HUMAN
Immunogen	Synthetic peptide taken within amino acid region 1-50 on human PDE10A2 protein.
Immunogen Region	1-50

Tissue Specificity	Abundant in the putamen and caudate nucleus regions of brain and testis, moderately expressed in the thyroid gland, pituitary gland, thalamus and cerebellum.
Post Translational Modifications	Isoform PDE10A2: Phosphorylated on Thr-16.
Function	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.
Protein Name	Camp And Camp-Inhibited Cgmp 3' -5'-Cyclic Phosphodiesterase 10a
Database Links	Reactome: R-HSA-418457 Reactome: R-HSA-418555
Cellular Localisation	Cytoplasm Cytosol
Alternative Antibody Names	Anti-Camp And Camp-Inhibited Cgmp 3' -5'-Cyclic Phosphodiesterase 10a antibody Anti-PDE10A antibody

Information sourced from Uniprot.org