Anti-PDCD1LG2 antibody [S5086RM] (STJ11105086)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Programmed Cell Death 1 Ligand 2 antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S5086RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDCD1LG2 |
| Gene ID | 80380 |
| Uniprot ID | PD1L2_HUMAN |
| Specificity | Recombinant protein of human PD-L2/CD273. |
Additional Info
| Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
| Database Links | Reactome: R-HSA-389948 |
| Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
| Alternative Antibody Names | Anti-Programmed Cell Death 1 Ligand 2 antibodyAnti-Pd-1 Ligand 2 antibodyAnti-Pd-L2 antibodyAnti-Pdcd1 Ligand 2 antibodyAnti-Programmed Death Ligand 2 antibodyAnti-Butyrophilin B7-Dc antibodyAnti-B7-Dc antibodyAnti-Cd Antigen Cd273 antibodyAnti-PDCD1LG2 antibodyAnti-B7DC antibodyAnti-CD273 antibodyAnti-PDCD1L2 antibodyAnti-PDL2 antibody |
Information sourced from Uniprot.org