Anti-PDCD10 antibody (40-120 aa) (STJ190375)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 40-120
General Information
| Short Description | Rabbit polyclonal anti-Programmed cell death protein 10 (40-120 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PDCD10 |
| Gene ID | 11235 |
| Uniprot ID | PDC10_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 40-120 |
| Immunogen Region | 40-120 aa |
| Specificity | PDC10 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. |
| Protein Name | Programmed Cell Death Protein 10Cerebral Cavernous Malformations 3 ProteinTf-1 Cell Apoptosis-Related Protein 15 |
| Database Links | |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideCell Membrane |
| Alternative Antibody Names | Anti-Programmed Cell Death Protein 10 antibodyAnti-Cerebral Cavernous Malformations 3 Protein antibodyAnti-Tf-1 Cell Apoptosis-Related Protein 15 antibodyAnti-PDCD10 antibodyAnti-CCM3 antibodyAnti-TFAR15 antibody |
Information sourced from Uniprot.org