Anti-PD L2 antibody [R02-2A1] (STJA0033784)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human PD-L2
General Information
| Short Description | Rabbit monoclonal anti-PD L2 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-2A1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PDCD1LG2 |
| Gene ID | 80380 |
| Uniprot ID | PD1L2_HUMAN |
| Immunogen | A synthetic peptide of human PD-L2 |
Additional Info
| Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
| Database Links | Reactome: R-HSA-389948 |
| Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
| Alternative Antibody Names | Anti-Programmed Cell Death 1 Ligand 2 antibodyAnti-Pd-1 Ligand 2 antibodyAnti-Pd-L2 antibodyAnti-Pdcd1 Ligand 2 antibodyAnti-Programmed Death Ligand 2 antibodyAnti-Butyrophilin B7-Dc antibodyAnti-B7-Dc antibodyAnti-Cd Antigen Cd273 antibodyAnti-PDCD1LG2 antibodyAnti-B7DC antibodyAnti-CD273 antibodyAnti-PDCD1L2 antibodyAnti-PDL2 antibody |
Information sourced from Uniprot.org