Anti-PCYT2 antibody (1-389) (STJ117504)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PCYT2 (1-389) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PCYT2 |
| Gene ID | 5833 |
| Uniprot ID | PCY2_HUMAN |
| Immunogen Region | 1-389 |
| Immunogen Sequence | MIRNGRGAAGGAEQPGPGGR RAVRVWCDGCYDMVHYGHSN QLRQARAMGDYLIVGVHTDE EIAKHKGPPVFTQEERYKMV QAIKWVDEVVPAAPYVTTLE TLDKYNCDFCVHGNDITLTV DGRDTYEEVKQAGRYRECKR TQGVSTTDLVGRMLLVTKAH HSSQEMSSEYREYADSFGKC PGGRNPWTGVSQFLQTSQKI IQFASGKEPQPGETVIYVAG AFDLFHIGHVDFLEKVHRL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-389 of human PCYT2 (NP_002852.1). |
Additional Info
| Tissue Specificity | Strongest expression in liver, heart, and skeletal muscle. |
| Function | Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway. Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis. |
| Protein Name | Ethanolamine-Phosphate CytidylyltransferaseCtp -Phosphoethanolamine CytidylyltransferasePhosphorylethanolamine Transferase |
| Database Links | Reactome: R-HSA-1483213 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Ethanolamine-Phosphate Cytidylyltransferase antibodyAnti-Ctp -Phosphoethanolamine Cytidylyltransferase antibodyAnti-Phosphorylethanolamine Transferase antibodyAnti-PCYT2 antibody |
Information sourced from Uniprot.org