Anti-PCSK1 antibody (125-175 aa) (STJ194864)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NEC1 at the amino acid range 125-175
General Information
| Short Description | Rabbit polyclonal anti-Neuroendocrine convertase 1 (125-175 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PCSK1 |
| Gene ID | 5122 |
| Uniprot ID | NEC1_HUMAN |
| Immunogen | Synthesized peptide derived from the human NEC1 at the amino acid range 125-175 |
| Immunogen Region | 125-175 aa |
| Specificity | This antibody detects endogenous levels of NEC1 at Human/Mouse/Rat |
Additional Info
| Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP. |
| Protein Name | Neuroendocrine Convertase 1Nec 1Prohormone Convertase 1Proprotein Convertase 1Pc1 |
| Database Links | Reactome: R-HSA-209952Reactome: R-HSA-264876Reactome: R-HSA-381771Reactome: R-HSA-400511Reactome: R-HSA-422085 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleLocalized In The Secretion Granules |
| Alternative Antibody Names | Anti-Neuroendocrine Convertase 1 antibodyAnti-Nec 1 antibodyAnti-Prohormone Convertase 1 antibodyAnti-Proprotein Convertase 1 antibodyAnti-Pc1 antibodyAnti-PCSK1 antibodyAnti-NEC1 antibody |
Information sourced from Uniprot.org