Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Neuroendocrine convertase 1 (125-175 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PCSK1 |
Gene ID: |
5122 |
Uniprot ID: |
NEC1_HUMAN |
Immunogen Region: |
125-175 aa |
Specificity: |
This antibody detects endogenous levels of NEC1 at Human/Mouse/Rat |
Immunogen: |
Synthesized peptide derived from the human NEC1 at the amino acid range 125-175 |
Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP. |
Protein Name | Neuroendocrine Convertase 1Nec 1Prohormone Convertase 1Proprotein Convertase 1Pc1 |
Database Links | Reactome: R-HSA-209952Reactome: R-HSA-264876Reactome: R-HSA-381771Reactome: R-HSA-400511Reactome: R-HSA-422085 |
Cellular Localisation | Cytoplasmic VesicleSecretory VesicleLocalized In The Secretion Granules |
Alternative Antibody Names | Anti-Neuroendocrine Convertase 1 antibodyAnti-Nec 1 antibodyAnti-Prohormone Convertase 1 antibodyAnti-Proprotein Convertase 1 antibodyAnti-Pc1 antibodyAnti-PCSK1 antibodyAnti-NEC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance