• STJ72418 (0. 01µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-PCBP1 antibody (234-247) (STJ72418)

SKU:
STJ72418-100

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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat/Dog/Pig/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-PCBP1 (234-247) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.01-0.03µg/ml
IHC-5µg/ml
ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PCBP1
Gene ID: 5093
Uniprot ID: PCBP1_HUMAN
Immunogen Region: 234-247
Accession Number: CAA55016.1
Immunogen Sequence: ADLAKLNQVARQQSH
Post Translational Modifications Phosphorylated.lowers poly(rC)-binding activity.
Function Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing. (Microbial infection) In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD.
Protein Name Poly(Rc-Binding Protein 1
Alpha-Cp1
Heterogeneous Nuclear Ribonucleoprotein E1
Hnrnp E1
Nucleic Acid-Binding Protein Sub2.3
Database Links Reactome: R-HSA-72163
Reactome: R-HSA-72203
Cellular Localisation Nucleus
Cytoplasm
Loosely Bound In The Nucleus
May Shuttle Between The Nucleus And The Cytoplasm
Alternative Antibody Names Anti-Poly(Rc-Binding Protein 1 antibody
Anti-Alpha-Cp1 antibody
Anti-Heterogeneous Nuclear Ribonucleoprotein E1 antibody
Anti-Hnrnp E1 antibody
Anti-Nucleic Acid-Binding Protein Sub2.3 antibody
Anti-PCBP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance