Anti-PCBP1 antibody (1-163aa) [AT2A10] (STJA0041676)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human PCBP1 (1-163aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-PCBP1 (1-163aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT2A10 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PCBP1 |
| Gene ID | 5093 |
| Uniprot ID | PCBP1_HUMAN |
| Accession Number | NP_006187 |
| Immunogen | Recombinant human PCBP1 (1-163aa) purified from E. coli |
| Immunogen Region | 1-163aa |
Additional Info
| Tissue Specificity | Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands. |
| Post Translational Modifications | Phosphorylated.lowers poly(rC)-binding activity. |
| Function | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing. (Microbial infection) In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD. |
| Protein Name | Poly(Rc-Binding Protein 1Alpha-Cp1Heterogeneous Nuclear Ribonucleoprotein E1Hnrnp E1Nucleic Acid-Binding Protein Sub2.3 |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-72203 |
| Cellular Localisation | NucleusCytoplasmLoosely Bound In The NucleusMay Shuttle Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-Poly(Rc-Binding Protein 1 antibodyAnti-Alpha-Cp1 antibodyAnti-Heterogeneous Nuclear Ribonucleoprotein E1 antibodyAnti-Hnrnp E1 antibodyAnti-Nucleic Acid-Binding Protein Sub2.3 antibodyAnti-PCBP1 antibody |
Information sourced from Uniprot.org