PCB antibody western blot HepG2 lysates STJA0036986

Anti-PCB antibody [R05-3B6] (STJA0036986)

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STJA0036986
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-PCB for use in WB, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ICC/IF
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R05-3B6
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
IF 1:50-1:200
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:PC
Gene ID:5091
Uniprot ID:PYC_HUMAN
Immunogen:A synthesized peptide derived from human PCB
Post Translational Modifications Acetylation of Lys-748 might play a role in catalytic activity regulation.
Function Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
Protein Name Pyruvate Carboxylase - Mitochondrial
Pyruvic Carboxylase
Pcb
Database Links Reactome: R-HSA-196780
Reactome: R-HSA-3371599
Reactome: R-HSA-70263
Reactome: R-HSA-70268
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Pyruvate Carboxylase - Mitochondrial antibody
Anti-Pyruvic Carboxylase antibody
Anti-Pcb antibody
Anti-PC antibody

Information sourced from Uniprot.org

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