Anti-PAX3 antibody (1-479) (STJ24909)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PAX3 (1-479) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAX3 |
| Gene ID | 5077 |
| Uniprot ID | PAX3_HUMAN |
| Immunogen Region | 1-479 |
| Immunogen Sequence | MTTLAGAVPRMMRPGPGQNY PRSGFPLEVSTPLGQGRVNQ LGGVFINGRPLPNHIRHKIV EMAHHGIRPCVISRQLRVSH GCVSKILCRYQETGSIRPGA IGGSKPKQVTTPDVEKKIEE YKRENPGMFSWEIRDKLLKD AVCDRNTVPSVSSISRILRS KFGKGEEEEADLERKEAEES EKKAKHSIDGILSERASAPQ SDEGSDIDSEPDLPLKRKQR RSRTTFTAEQLEELER |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human PAX3 (NP_852122.1). |
Additional Info
| Function | Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10. |
| Protein Name | Paired Box Protein Pax-3Hup2 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9834899Reactome: R-HSA-9856649 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Box Protein Pax-3 antibodyAnti-Hup2 antibodyAnti-PAX3 antibodyAnti-HUP2 antibody |
Information sourced from Uniprot.org