| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PATZ1 |
| Gene ID: | 23598 |
| Uniprot ID: | PATZ1_HUMAN |
| Immunogen Region: | 250-350 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human PATZ1 (NP_055138.2). |
| Immunogen Sequence: | PFPSVASSAPPLTGKRGRGR PRKANLLDSMFGSPGGLREA GILPCGLCGKVFTDANRLRQ HEAQHGVTSLQLGYIDLPPP RLGENGLPISEDPDGPRKRS R |
| Tissue Specificity | Ubiquitous. |
| Function | Transcriptional regulator that plays a role in many biological processes such as embryogenesis, senescence, T-cell development or neurogenesis. Interacts with the TP53 protein to control genes that are important in proliferation and in the DNA-damage response. Mechanistically, the interaction inhibits the DNA binding and transcriptional activity of TP53/p53. Part of the transcriptional network modulating regulatory T-cell development and controls the generation of the regulatory T-cell pool under homeostatic conditions. (Microbial infection) Plays a positive role in viral cDNA synthesis. |
| Protein Name | Poz- - At Hook- - And Zinc Finger-Containing Protein 1 Btb/Poz Domain Zinc Finger Transcription Factor Protein Kinase A Ri Subunit Alpha-Associated Protein Zinc Finger And Btb Domain-Containing Protein 19 Zinc Finger Protein 278 Zinc Finger Sarcoma Gene Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Poz- - At Hook- - And Zinc Finger-Containing Protein 1 antibody Anti-Btb/Poz Domain Zinc Finger Transcription Factor antibody Anti-Protein Kinase A Ri Subunit Alpha-Associated Protein antibody Anti-Zinc Finger And Btb Domain-Containing Protein 19 antibody Anti-Zinc Finger Protein 278 antibody Anti-Zinc Finger Sarcoma Gene Protein antibody Anti-PATZ1 antibody Anti-PATZ antibody Anti-RIAZ antibody Anti-ZBTB19 antibody Anti-ZNF278 antibody Anti-ZSG antibody |
Information sourced from Uniprot.org