Anti-PATL1 antibody (263-313 aa) (STJ193795)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human PATL1 at the amino acid range 263-313
General Information
| Short Description | Rabbit polyclonal anti-Protein PAT1 homolog 1 (263-313 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PATL1 |
| Gene ID | 219988 |
| Uniprot ID | PATL1_HUMAN |
| Immunogen | Synthesized peptide derived from the human PATL1 at the amino acid range 263-313 |
| Immunogen Region | 263-313 aa |
| Specificity | This antibody detects endogenous levels of PATL1 at Human/Mouse/Rat |
Additional Info
| Function | RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs. Acts as a scaffold protein that connects deadenylation and decapping machinery. Required for cytoplasmic mRNA processing body (P-body) assembly. (Microbial infection) In case of infection, required for translation and replication of hepatitis C virus (HCV). |
| Protein Name | Protein Pat1 Homolog 1Pat1-Like Protein 1Protein Pat1 Homolog BPat1bHpat1b |
| Database Links | Reactome: R-HSA-430039 |
| Cellular Localisation | CytoplasmP-BodyNucleusPml BodyNucleus SpecklePredominantly CytoplasmicShuttles Between The Nucleus And The Cytoplasm In A Crm1-Dependent MannerEnriched In Splicing SpecklesLocalization To Nuclear Foci And Speckles Requires Active TranscriptionExcluded From The Nucleolus |
| Alternative Antibody Names | Anti-Protein Pat1 Homolog 1 antibodyAnti-Pat1-Like Protein 1 antibodyAnti-Protein Pat1 Homolog B antibodyAnti-Pat1b antibodyAnti-Hpat1b antibodyAnti-PATL1 antibodyAnti-OK antibodyAnti-KNS-cl.5 antibody |
Information sourced from Uniprot.org