Anti-PARD6B antibody (300-350) (STJ506125)

Name: Anti-PARD6B antibody (300-350) (STJ506125)
SKU: STJ506125-100
Price: 400.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

ImmunogenSynthetic peptide corresponding to amino acids within region 300-350 on human Partitioning Defective 6 homolog beta.

STJ506125-100

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Short Description	Rabbit polyclonal antibody anti-PARD6B (300-350) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Applications	ELISA/IP/WB
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	0.5-1.5 µg/µl
Purification	Affinity Purified
Dilution Range	WB: 1:500-1:5, 000 ELISA: 1:50, 000 IP: 1:200
Formulation	Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol	PARD6B
Gene ID	84612
Uniprot ID	PAR6B_HUMAN
Immunogen	Synthetic peptide corresponding to amino acids within region 300-350 on human Partitioning Defective 6 homolog beta.
Immunogen Region	300-350

Tissue Specificity	Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Function	Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Protein Name	Partitioning Defective 6 Homolog Beta Par-6 Beta Par-6b
Database Links	Reactome: R-HSA-420029 Reactome: R-HSA-9013424
Cellular Localisation	Cytoplasm Cell Membrane Cell Junction Tight Junction
Alternative Antibody Names	Anti-Partitioning Defective 6 Homolog Beta antibody Anti-Par-6 Beta antibody Anti-Par-6b antibody Anti-PARD6B antibody Anti-PAR6B antibody

Information sourced from Uniprot.org