Anti-PARD6B antibody (300-350) {FITC} (STJ506127)

SKU:
STJ506127-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PARD6B (300-350) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PARD6B
Gene ID: 84612
Uniprot ID: PAR6B_HUMAN
Immunogen Region: 300-350
Immunogen: Synthetic peptide corresponding to amino acids within region 300-350 on human Partitioning Defective 6 homolog beta.
Tissue Specificity Expressed in pancreas and in both adult and fetal kidney. Weakly expressed in placenta and lung. Not expressed in other tissues.
Function Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Protein Name Partitioning Defective 6 Homolog Beta
Par-6 Beta
Par-6b
Database Links Reactome: R-HSA-420029
Reactome: R-HSA-9013424
Cellular Localisation Cytoplasm
Cell Membrane
Cell Junction
Tight Junction
Alternative Antibody Names Anti-Partitioning Defective 6 Homolog Beta antibody
Anti-Par-6 Beta antibody
Anti-Par-6b antibody
Anti-PARD6B antibody
Anti-PAR6B antibody

Information sourced from Uniprot.org

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