| Host: |
Rabbit |
| Applications: |
CM/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PAR3 (1-100) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.50-0.75 µg/µl |
| Dilution Range: |
WB: 1:5, 000DB: 1:12, 000ELISA: 1:12, 000IP: 1:200IHC: 1:200ICC: 1:200IF: 1:200CFM: 1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
F2rl3 |
| Gene ID: |
14065 |
| Uniprot ID: |
PAR4_MOUSE |
| Immunogen Region: |
1-100 |
| Immunogen: |
Synthetic peptide taken within amino acid region 1-100 on mouse Proteinase-activated receptor 3 protein. |
| Tissue Specificity | Highly expressed in the spleen. Slight expression in the heart, lung, skeletal muscle and kidney. No detectable expression in brain, liver or testis. Also detected in platelets. |
| Post Translational Modifications | A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. |
| Function | Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. |
| Protein Name | Proteinase-Activated Receptor 4Par-4Coagulation Factor Ii Receptor-Like 3Thrombin Receptor-Like 3 |
| Database Links | Reactome: R-MMU-375276Reactome: -MMU-416476Reactome: -MMU-456926 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Proteinase-Activated Receptor 4 antibodyAnti-Par-4 antibodyAnti-Coagulation Factor Ii Receptor-Like 3 antibodyAnti-Thrombin Receptor-Like 3 antibodyAnti-F2rl3 antibodyAnti-Par4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
