Anti-PAPSS2 antibody [3H10] (STJA0032745)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenPurified recombinant human PAPSS2 protein fragments expressed in E.coli.
General Information
| Short Description | Mouse monoclonal anti-PAPSS2 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 3H10 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PAPSS2 |
| Gene ID | 9060 |
| Uniprot ID | PAPS2_HUMAN |
| Immunogen | Purified recombinant human PAPSS2 protein fragments expressed in E.coli. |
Additional Info
| Tissue Specificity | Expressed in cartilage and adrenal gland. |
| Function | Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate/PAPS, the activated sulfate donor used by sulfotransferases. In mammals, PAPS is the sole source of sulfate while APS appears to only be an intermediate in the sulfate-activation pathway. Plays indirectly an important role in skeletogenesis during postnatal growth. |
| Protein Name | Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2Paps Synthase 2Papss 2Sulfurylase Kinase 2Sk 2Sk2 Includes - Sulfate AdenylyltransferaseAtp-SulfurylaseSulfate Adenylate TransferaseSat - Adenylyl-Sulfate Kinase3'-Phosphoadenosine-5'-Phosphosulfate SynthaseAps KinaseAdenosine-5'-Phosphosulfate 3'-PhosphotransferaseAdenylylsulfate 3'-Phosphotransferase |
| Database Links | Reactome: R-HSA-174362Reactome: R-HSA-2408550Reactome: R-HSA-3560796 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 2 antibodyAnti-Paps Synthase 2 antibodyAnti-Papss 2 antibodyAnti-Sulfurylase Kinase 2 antibodyAnti-Sk 2 antibodyAnti-Sk2 Includes - Sulfate Adenylyltransferase antibodyAnti-Atp-Sulfurylase antibodyAnti-Sulfate Adenylate Transferase antibodyAnti-Sat - Adenylyl-Sulfate Kinase antibodyAnti-3'-Phosphoadenosine-5'-Phosphosulfate Synthase antibodyAnti-Aps Kinase antibodyAnti-Adenosine-5'-Phosphosulfate 3'-Phosphotransferase antibodyAnti-Adenylylsulfate 3'-Phosphotransferase antibodyAnti-PAPSS2 antibodyAnti-ATPSK2 antibody |
Information sourced from Uniprot.org