| Short Description : | Rabbit polyclonal Poly (A Polymerase Alpha antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB, 1:3000-1:12000ELISA, Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAPOLA |
| Gene ID: | 10914 |
| Uniprot ID: | PAPOA_HUMAN |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Immunogen Sequence: | Human |
| Function | Polymerase that creates the 3'-poly(A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus. |
| Protein Name | Poly(A Polymerase AlphaPap-AlphaPolynucleotide Adenylyltransferase Alpha |
| Database Links | Reactome: R-HSA-72187Reactome: R-HSA-72203Reactome: R-HSA-73856Reactome: R-HSA-77595 |
| Cellular Localisation | CytoplasmNucleusThe 90 Kda Form Is Nuclear While The 100 Kda And The 106 Kda Forms Are Both Nuclear And Cytoplasmic |
| Alternative Antibody Names | Anti-Poly(A Polymerase Alpha antibodyAnti-Pap-Alpha antibodyAnti-Polynucleotide Adenylyltransferase Alpha antibodyAnti-PAPOLA antibodyAnti-PAP antibody |
Information sourced from Uniprot.org
