• Western blot with Anti-PANX1 Antibody (STJ502101) on 60-65ug rat spinal cord at 1:500 dilution in buffer from a 12% SDS gel.

Anti-PANX1 antibody (STJ502101)

SKU:
STJ502101-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PANX1 is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.55 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PANX1
Gene ID: 24145
Uniprot ID: PANX1_HUMAN
Immunogen: Synthetic peptide taken within amino acid region from human Pannexin 1 protein
Tissue Specificity Widely expressed. Highest expression is observed in oocytes and brain. Detected at very low levels in sperm cells.
Post Translational Modifications S-nitrosylation inhibits channel currents and ATP release. N-glycosylation may play a role in cell surface targeting. Exists in three glycosylation states: non-glycosylated (GLY0), high-mannose glycosylated (GLY1), and fully mature glycosylated (GLY2).
Function Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Plays a critical role in oogenesis.
Protein Name Pannexin-1
Database Links Reactome: R-HSA-112303
Reactome: R-HSA-844456
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Junction
Gap Junction
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Pannexin-1 antibody
Anti-PANX1 antibody
Anti-MRS1 antibody
Anti-UNQ2529 antibody
Anti-PRO6028 antibody

Information sourced from Uniprot.org

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