Anti-Pallidin antibody (C-Term) (STJ70364)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Pallidin (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 23-24kDa band observed in lysates of cell line A431 (calculated MW of 19.7kDa according to NP_036520.1). In transfected HEK293 transiently expressing PLDN a band of approx. 28kD |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | BLOC1S6 |
| Gene ID | 26258 |
| Uniprot ID | BL1S6_HUMAN |
| Accession Number | NP_036520.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | EREKQLTARPAKRM |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. |
| Protein Name | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6Bloc-1 Subunit 6Pallid Protein HomologPallidinSyntaxin 13-Interacting Protein |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinIt Can Exist As A Soluble Protein As Well As A Peripheral Membrane Protein |
| Alternative Antibody Names | Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6 antibodyAnti-Bloc-1 Subunit 6 antibodyAnti-Pallid Protein Homolog antibodyAnti-Pallidin antibodyAnti-Syntaxin 13-Interacting Protein antibodyAnti-BLOC1S6 antibodyAnti-PA antibodyAnti-PLDN antibody |
Information sourced from Uniprot.org