Anti-PAK1IP1 antibody (STJ191890)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-p21-activated protein kinase-interacting protein 1 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAK1IP1 |
| Gene ID | 55003 |
| Uniprot ID | PK1IP_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | PK1IP Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly. |
| Protein Name | P21-Activated Protein Kinase-Interacting Protein 1Pak/Plc-Interacting Protein 1Hpip1Pak1-Interacting Protein 1Wd Repeat-Containing Protein 84 |
| Database Links | |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-P21-Activated Protein Kinase-Interacting Protein 1 antibodyAnti-Pak/Plc-Interacting Protein 1 antibodyAnti-Hpip1 antibodyAnti-Pak1-Interacting Protein 1 antibodyAnti-Wd Repeat-Containing Protein 84 antibodyAnti-PAK1IP1 antibodyAnti-PIP1 antibodyAnti-WDR84 antibody |
Information sourced from Uniprot.org