Anti-PAH antibody (110-452) (STJ11105611)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal Phenylalanine-4-Hydroxylase (110-452) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAH |
| Gene ID | 5053 |
| Uniprot ID | PH4H_HUMAN |
| Immunogen Region | 110-452 |
| Immunogen Sequence | SRDKKKDTVPWFPRTIQELD RFANQILSYGAELDADHPGF KDPVYRARRKQFADIAYNYR HGQPIPRVEYMEEEKKTWGT VFKTLKSLYKTHACYEYNHI FPLLEKYCGFHEDNIPQLED VSQFLQTCTGFRLRPVAGLL SSRDFLGGLAFRVFHCTQYI RHGSKPMYTPEPDICHELLG HVPLFSDRSFAQFSQEIGLA SLGAPDEYIEKLATIYWFTV EFGLCKQGDSIKAYGAGLL |
| Specificity | Recombinant Protein corresponding to a sequence within amino acids 110-452 of human PAH (NP_000268.1). |
Additional Info
| Post Translational Modifications | Phosphorylation at Ser-16 increases basal activity and facilitates activation by the substrate phenylalanine. |
| Function | Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. |
| Protein Name | Phenylalanine-4-HydroxylasePahPhe-4-Monooxygenase |
| Database Links | Reactome: R-HSA-2160456Reactome: R-HSA-8964208 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Phenylalanine-4-Hydroxylase antibodyAnti-Pah antibodyAnti-Phe-4-Monooxygenase antibodyAnti-PAH antibody |
Information sourced from Uniprot.org