| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PAH (1-290) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PAH |
| Gene ID: |
5053 |
| Uniprot ID: |
PH4H_HUMAN |
| Immunogen Region: |
1-290 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human PAH (NP_000268.1). |
| Immunogen Sequence: |
MSTAVLENPGLGRKLSDFGQ ETSYIEDNCNQNGAISLIFS LKEEVGALAKVLRLFEENDV NLTHIESRPSRLKKDEYEFF THLDKRSLPALTNIIKILRH DIGATVHELSRDKKKDTVPW FPRTIQELDRFANQILSYGA ELDADHPGFKDPVYRARRKQ FADIAYNYRHGQPIPRVEYM EEEKKTWGTVFKTLKSLYKT HACYEYNHIFPLLEKYCGFH EDNIPQLEDVSQFLQTCTG |
| Post Translational Modifications | Phosphorylation at Ser-16 increases basal activity and facilitates activation by the substrate phenylalanine. |
| Function | Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine. |
| Protein Name | Phenylalanine-4-HydroxylasePahPhe-4-Monooxygenase |
| Database Links | Reactome: R-HSA-2160456Reactome: R-HSA-8964208 |
| Alternative Antibody Names | Anti-Phenylalanine-4-Hydroxylase antibodyAnti-Pah antibodyAnti-Phe-4-Monooxygenase antibodyAnti-PAH antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MSH6 knockout (KO) HeLa cells, using [KO Validated] MSH6 Rabbit polyclonal antibody (STJ119980) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98765/382817/STJ119980_1__09948.1713151312.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MSH6 knockout (KO) HeLa cells, using [KO Validated] MSH6 Rabbit polyclonal antibody (STJ119980) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")
