Anti-PAFAH2 antibody (STJA0007422)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PAFAH2
General Information
| Short Description | Rabbit polyclonal anti-Platelet-activating factor acetylhydrolase 2, cytoplasmic for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAFAH2 |
| Gene ID | 5051 |
| Uniprot ID | PAFA2_HUMAN |
| Immunogen | Synthesized peptide derived from human PAFAH2 |
| Specificity | This antibody detects endogenous levels of PAFAH2 at Human, Mouse, Rat |
Additional Info
| Function | Catalyzes the hydrolyze of the acetyl group at the sn-2 position of platelet-activating factor (PAF) and its analogs, leading to their inactivation. Hydrolyzes propionyl and butyroyl moieties approximately half as effectively as PAF. Also catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Has a marked selectivity for phospholipids with short acyl chains at the sn-2 position. |
| Protein Name | Platelet-Activating Factor Acetylhydrolase 2 - CytoplasmicPaf -Lysophospholipid TransacetylasePaf -Sphingosine TransacetylasePlatelet-Activating Factor Acetyltransferase Pafah2Serine-Dependent Phospholipase A2Sd-Pla2Hsd-Pla2 |
| Database Links | Reactome: R-HSA-418346 |
| Cellular Localisation | CytoplasmMembraneLipid-AnchorEndoplasmic Reticulum MembraneIn Resting CellsLocalizes To Intracellular Membranes And CytoplasmTranslocates From The Cytoplasm To Intracellular Membranes Upon Oxidative Stress |
| Alternative Antibody Names | Anti-Platelet-Activating Factor Acetylhydrolase 2 - Cytoplasmic antibodyAnti-Paf -Lysophospholipid Transacetylase antibodyAnti-Paf -Sphingosine Transacetylase antibodyAnti-Platelet-Activating Factor Acetyltransferase Pafah2 antibodyAnti-Serine-Dependent Phospholipase A2 antibodyAnti-Sd-Pla2 antibodyAnti-Hsd-Pla2 antibodyAnti-PAFAH2 antibody |
Information sourced from Uniprot.org