Anti-PAEP antibody (STJ192134)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Glycodelin for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAEP |
| Gene ID | 5047 |
| Uniprot ID | PAEP_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | PAEP Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Four distinct glycoforms A, C, F and S arise from different N-linked oligosaccharide chains at amino acid residues Asn-46 and Asn-81. Glycodelin-A and -F are taken up by the cumulus cells in which partial deglycosylation takes place to produce glycodelin-C. |
| Function | Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities. Glycodelin-C stimulates binding of spermatozoa to the zona pellucida. Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa. Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa. |
| Protein Name | GlycodelinGdPlacental Protein 14Pp14Pregnancy-Associated Endometrial Alpha-2 GlobulinPaegPegProgestagen-Associated Endometrial ProteinProgesterone-Associated Endometrial ProteinZona-Binding Inhibitory Factor-1Zif-1 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Glycodelin antibodyAnti-Gd antibodyAnti-Placental Protein 14 antibodyAnti-Pp14 antibodyAnti-Pregnancy-Associated Endometrial Alpha-2 Globulin antibodyAnti-Paeg antibodyAnti-Peg antibodyAnti-Progestagen-Associated Endometrial Protein antibodyAnti-Progesterone-Associated Endometrial Protein antibodyAnti-Zona-Binding Inhibitory Factor-1 antibodyAnti-Zif-1 antibodyAnti-PAEP antibody |
Information sourced from Uniprot.org