Anti-PACSIN3 antibody [PT0794R] (STJA0039355)

SKU:
STJA0039355
€180.00 - €648.00
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Host: Rabbit
Applications: WB/IHC/IF/ICC/FC/IP
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3 for use in WB, IHC, IF, ICC, FC and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : PT0794R
Conjugation: Unconjugated
Isotype: IgGk
Formulation: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification: Protein A
Dilution Range: WB 1:1000-5000
IHC 1:100-300
ICC/IF 1:100-300
FC 1:100-300
IP 1:50-100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PACSIN3
Gene ID: 29763
Uniprot ID: PACN3_HUMAN
Specificity: Endogenous
Post Translational Modifications Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
Function Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.
Protein Name Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3
Sh3 Domain-Containing Protein 6511
Database Links Reactome: R-HSA-8856828
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Detected At The Inner Aspect Of The Plasma Membrane In Myotubes
Alternative Antibody Names Anti-Protein Kinase C And Casein Kinase Substrate In Neurons Protein 3 antibody
Anti-Sh3 Domain-Containing Protein 6511 antibody
Anti-PACSIN3 antibody

Information sourced from Uniprot.org