Anti-PACE4 antibody (Internal) (STJ71748)

SKU:
STJ71748-100

Shipping:
Free Shipping
Current Stock:
Host: Goat
Applications: Pep-ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-PACE4 (Internal) is suitable for use in ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-3.75µg/ml
ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: PCSK6
Gene ID: 5046
Uniprot ID: PCSK6_HUMAN
Immunogen Region: Internal
Accession Number: NP_002561.1; NP_612192.1; NP_612195.1; NP_612197.1; NP_612196.1; NP_612198.2; NP_612193.1; NP_612194.1
Specificity: This antibody is expected to recognize reported isoforms a, b, g, h (NP_002561.1; NP_612192.1; NP_612193.1; NP_612194.1 resp.).
Immunogen Sequence: PDCEPGTYFDSE
Function Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXXKRR consensus motif. Likely functions in the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues.
Protein Name Proprotein Convertase Subtilisin/Kexin Type 6
Paired Basic Amino Acid Cleaving Enzyme 4
Subtilisin-Like Proprotein Convertase 4
Spc4
Subtilisin/Kexin-Like Protease Pace4
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-167060
Reactome: R-HSA-6809371
Reactome: R-HSA-8963889
Cellular Localisation Isoform Pace4a-I: Secreted
Isoform Pace4a-Ii: Secreted
Isoform Pace4c: Endoplasmic Reticulum
Not Secreted
Remains Probably In Zymogen Form In Endoplasmic Reticulum
Isoform Pace4cs: Endoplasmic Reticulum
Isoform Pace4e-I: Endomembrane System
Peripheral Membrane Protein
Retained Intracellularly Probably Through A Hydrophobic Cluster In Their C-Terminus
Isoform Pace4e-Ii: Endomembrane System
Isoform Pace4b: Secreted
Alternative Antibody Names Anti-Proprotein Convertase Subtilisin/Kexin Type 6 antibody
Anti-Paired Basic Amino Acid Cleaving Enzyme 4 antibody
Anti-Subtilisin-Like Proprotein Convertase 4 antibody
Anti-Spc4 antibody
Anti-Subtilisin/Kexin-Like Protease Pace4 antibody
Anti-PCSK6 antibody
Anti-PACE4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance