| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Proteasomal ATPase-associated factor 1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAAF1 |
| Gene ID: | 80227 |
| Uniprot ID: | PAAF1_HUMAN |
| Specificity: | This antibody detects endogenous levels of PAAF1 at Human |
| Immunogen: | Synthesized peptide derived from human PAAF1 |
| Function | Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation. |
| Protein Name | Proteasomal Atpase-Associated Factor 1Protein G-16Wd Repeat-Containing Protein 71 |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Proteasomal Atpase-Associated Factor 1 antibodyAnti-Protein G-16 antibodyAnti-Wd Repeat-Containing Protein 71 antibodyAnti-PAAF1 antibodyAnti-WDR71 antibody |
Information sourced from Uniprot.org
