![Anti-p57 kip2 antibody [SM5048] (STJA0005048)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/180105/403376/STJA0005048_1__72870.1738950441.png?c=1 "Anti-p57 kip2 antibody [SM5048] (STJA0005048)")
![Anti-p57 kip2 antibody [SM5048] (STJA0005048)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/180105/403376/STJA0005048_1__72870.1738950441.png?c=1 "Anti-p57 kip2 antibody [SM5048] (STJA0005048)")
Anti-p57 kip2 antibody [SM5048] (STJA0005048)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
ImmunogenSynthesized peptide derived from human p57kip2
General Information
| Short Description | Mouse monoclonal anti-p57 kip2 for use in IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SM5048 |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC/IF (H) 1:200-1:500 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage Instruction | Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Target Information
| Gene Symbol | CDKN1C |
| Gene ID | 1028 |
| Uniprot ID | CDN1C_HUMAN |
| Immunogen | Synthesized peptide derived from human p57kip2 |
Additional Info
| Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
| Protein Name | Cyclin-Dependent Kinase Inhibitor 1cCyclin-Dependent Kinase Inhibitor P57P57kip2 |
| Database Links | Reactome: R-HSA-69231Reactome: R-HSA-9661069 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cyclin-Dependent Kinase Inhibitor 1c antibodyAnti-Cyclin-Dependent Kinase Inhibitor P57 antibodyAnti-P57kip2 antibodyAnti-CDKN1C antibodyAnti-KIP2 antibody |
Information sourced from Uniprot.org