Host: |
Rabbit |
Applications: |
IHC-P |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-P504s is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
13H4 |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Dilution Range: |
IHC-P 1:50-1:200 |
Storage Instruction: |
Store at 2-8°C upon receipt. |
Background | Alpha-Methylacyl-CoA Racemase (also known as AMACR or P504s) is an essential enzyme in the Beta oxidation of branched-chain fatty acids. AMACR over-expression has been demonstrated in several cancers including colorectal, prostate, ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma. Staining with the antibody to this enzyme has been useful in identifying prostate carcinoma and prostatic intraepithelial neoplasia, as well as atypical adenomatous hyperplasia in formalin-fixed paraffinized tissue in morphologically difficult cases. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance