Anti-p47phox-Mouse antibody (Internal) (STJ72451)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-p47phox-Mouse (Internal) is suitable for use in ELISA, Western Blot and Immunofluorescence research applications. |
| Applications | Pep-ELISA/WB/IF |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:2000.WB: Approx 48kDa band observed in lysates of cell line Daudi and in preliminary testing of Mouse Spleen lysate (calculated MW of 44.7kDa according to Human NP_000256.4. This molecular weigh |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | NCF1 |
| Gene ID | 653361 |
| Uniprot ID | NCF1_HUMAN |
| Accession Number | NP_035006.3 |
| Immunogen Region | Internal |
| Immunogen Sequence | DEAEDPDPNYAGEP |
Additional Info
| Post Translational Modifications | Phosphorylated by PRKCD.phosphorylation induces activation of NCF1 and NADPH oxidase activity. |
| Function | NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production). |
| Protein Name | Neutrophil Cytosol Factor 1Ncf-147 Kda Autosomal Chronic Granulomatous Disease Protein47 Kda Neutrophil Oxidase FactorNcf-47kNeutrophil Nadph Oxidase Factor 1Nox Organizer 2Nox-Organizing Protein 2Sh3 And Px Domain-Containing Protein 1aP47-Phox |
| Database Links | Reactome: R-HSA-1222556Reactome: R-HSA-1236973Reactome: R-HSA-3299685Reactome: R-HSA-4420097Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423 |
| Cellular Localisation | CytoplasmCytosolMembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Neutrophil Cytosol Factor 1 antibodyAnti-Ncf-1 antibodyAnti-47 Kda Autosomal Chronic Granulomatous Disease Protein antibodyAnti-47 Kda Neutrophil Oxidase Factor antibodyAnti-Ncf-47k antibodyAnti-Neutrophil Nadph Oxidase Factor 1 antibodyAnti-Nox Organizer 2 antibodyAnti-Nox-Organizing Protein 2 antibodyAnti-Sh3 And Px Domain-Containing Protein 1a antibodyAnti-P47-Phox antibodyAnti-NCF1 antibodyAnti-NOXO2 antibodyAnti-SH3PXD1A antibody |
Information sourced from Uniprot.org