Anti-P2RY1 antibody (274-373) (STJ110019)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal P2RY1 (274-373) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | P2RY1 |
| Gene ID | 5028 |
| Uniprot ID | P2RY1_HUMAN |
| Immunogen Region | 274-373 |
| Immunogen Sequence | IPFHVMKTMNLRARLDFQTP AMCAFNDRVYATYQVTRGLA SLNSCVDPILYFLAGDTFRR RLSRATRKASRRSEANLQSK SEDMTLNILPEFKQNGDTSL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 274-373 of human P2RY1 (NP_002554.1). |
Additional Info
| Function | Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. |
| Protein Name | P2y Purinoceptor 1P2y1Adp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-416476Reactome: R-HSA-417957Reactome: R-HSA-418592 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-P2y Purinoceptor 1 antibodyAnti-P2y1 antibodyAnti-Adp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RY1 antibody |
Information sourced from Uniprot.org