Anti-P2RX3 antibody (328-397) (STJ114831)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal P2RX3 (328-397) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | P2RX3 |
| Gene ID | 5024 |
| Uniprot ID | P2RX3_HUMAN |
| Immunogen Region | 328-397 |
| Immunogen Sequence | AFTSVGVGTVLCDIILLNFL KGADQYKAKKFEEVNETTLK IAALTNPVYPSDQTTAEKQS TDSGAFSIGH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 328-397 of human P2RX3 (NP_002550.2). |
Additional Info
| Function | Extracellular ATP-activated non-selective cation channel. Plays particularly important role in sensory neurons where its activation is critical for gustatory, nociceptive responses, visceral reflexes and sensory hypersensitization. |
| Protein Name | P2x Purinoceptor 3P2x3Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-139853Reactome: R-HSA-418346 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalizes To Neuronal Cell Body Of Sensory Neurons |
| Alternative Antibody Names | Anti-P2x Purinoceptor 3 antibodyAnti-P2x3 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX3 antibody |
Information sourced from Uniprot.org