| Short Description : | Rabbit polyclonal anti-P2RX2 for use in IHC and WB in Mouse, Human and Guinea Pig samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Mouse/Human/Guinea Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:2000 to 1:4000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | P2RX2 |
| Gene ID: | 22953 |
| Uniprot ID: | P2RX2_HUMAN |
| Immunogen: | A synthetic peptide from human P2RX2conjugated to blue carrier protein was used as the antigen. |
| Specificity: | Specific for P2RX2. |
| Function | ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle. |
| Protein Name | P2x Purinoceptor 2P2x2Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-139853Reactome: R-HSA-418346 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalizes To The Apical Membranes Of Hair Cells In The Organ Of Corti |
| Alternative Antibody Names | Anti-P2x Purinoceptor 2 antibodyAnti-P2x2 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX2 antibodyAnti-P2X2 antibody |
Information sourced from Uniprot.org
