| Tissue Specificity | Expressed in both the central and peripheral nervous system, as well as in the pituitary gland. |
| Function | ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle. |
| Protein Name | P2x Purinoceptor 2P2x2Atp ReceptorPurinergic Receptor |
| Database Links | Reactome: R-HSA-139853Reactome: R-HSA-418346 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalizes To The Apical Membranes Of Hair Cells In The Organ Of Corti |
| Alternative Antibody Names | Anti-P2x Purinoceptor 2 antibodyAnti-P2x2 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX2 antibodyAnti-P2X2 antibody |
Information sourced from Uniprot.org
