Anti-P-Cadherin antibody (N-Term) [M596] (STJA0041135)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenClone (M596) was generated from a recombinant protein containing amino acids in the N-terminal region of human P-Cadherin. This sequence is highly conserved in mouse and rat P-cadherin.
General Information
| Short Description | Mouse monoclonal anti-P-Cadherin (N-Term) for use in ELISA, WB and ICC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | M596 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | Protein A Purified |
| Dilution Range | WB 1:1000ICC 1:100 |
| Formulation | PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
| Storage Instruction | Storage at-20ยฐC is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at-20ยฐC. |
Target Information
| Gene Symbol | CDH3 |
| Gene ID | 1001 |
| Uniprot ID | CADH3_HUMAN |
| Immunogen | Clone (M596) was generated from a recombinant protein containing amino acids in the N-terminal region of human P-Cadherin. This sequence is highly conserved in mouse and rat P-cadherin. |
| Immunogen Region | N-Term |
| Immunogen Sequence | Human |
| Specificity | The P-cadherin antibody detects a 120 kDa* protein corresponding to endogenous P-Cadherin expressed in human A431 cells. |
Additional Info
| Tissue Specificity | Expressed in some normal epithelial tissues and in some carcinoma cell lines. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-3Placental CadherinP-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-3 antibodyAnti-Placental Cadherin antibodyAnti-P-Cadherin antibodyAnti-CDH3 antibodyAnti-CDHP antibody |
Information sourced from Uniprot.org