Anti-OTC antibody [SRM14799] (STJ11109529)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal OTC antibody for use in WB, IF-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM14799 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:1000-1:5000IF-P, 1:50-1:200ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OTC |
| Gene ID | 5009 |
| Uniprot ID | OTC_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Tissue Specificity | Mainly expressed in liver and intestinal mucosa. |
| Post Translational Modifications | Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. |
| Function | Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. |
| Protein Name | Ornithine Transcarbamylase - MitochondrialOtcaseOrnithine Carbamoyltransferase - Mitochondrial |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-70635 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Ornithine Transcarbamylase - Mitochondrial antibodyAnti-Otcase antibodyAnti-Ornithine Carbamoyltransferase - Mitochondrial antibodyAnti-OTC antibody |
Information sourced from Uniprot.org