| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/FC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-OSMR (Internal) is suitable for use in ELISA, Western Blot and Flow Cytometry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
FC-Flow cytometric analysis of HeLa cells. 10ug/mlELISA-antibody detection limit dilution 1:128000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
OSMR |
| Gene ID: |
9180 |
| Uniprot ID: |
OSMR_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_003990.1; NP_001161827.1; NP_001310435.1; NP_001310436.1 |
| Specificity: |
The immunizing peptide represents part of the extracellular domain. |
| Immunogen Sequence: |
QIHGEQLDPHVT |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Protein Name | Oncostatin-M-Specific Receptor Subunit BetaInterleukin-31 Receptor Subunit BetaIl-31 Receptor Subunit BetaIl-31r Subunit BetaIl-31r-BetaIl-31rb |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Oncostatin-M-Specific Receptor Subunit Beta antibodyAnti-Interleukin-31 Receptor Subunit Beta antibodyAnti-Il-31 Receptor Subunit Beta antibodyAnti-Il-31r Subunit Beta antibodyAnti-Il-31r-Beta antibodyAnti-Il-31rb antibodyAnti-OSMR antibodyAnti-OSMRB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
