Anti-OSMR antibody (Internal) (STJ72178)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-OSMR (Internal) is suitable for use in ELISA, Western Blot and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/FC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 125kDa band observed in lysates of cell line U937 and approx 70+125kDa in lysates of cell line A431 and HepG2 (calculated MW of 111kDa according to NP_003990.1 (isoform 1) and |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | OSMR |
| Gene ID | 9180 |
| Uniprot ID | OSMR_HUMAN |
| Accession Number | NP_003990.1; NP_001161827.1; NP_001310435.1; NP_001310436.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | QIHGEQLDPHVT |
| Specificity | The immunizing peptide represents part of the extracellular domain. |
Additional Info
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Protein Name | Oncostatin-M-Specific Receptor Subunit BetaInterleukin-31 Receptor Subunit BetaIl-31 Receptor Subunit BetaIl-31r Subunit BetaIl-31r-BetaIl-31rb |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Oncostatin-M-Specific Receptor Subunit Beta antibodyAnti-Interleukin-31 Receptor Subunit Beta antibodyAnti-Il-31 Receptor Subunit Beta antibodyAnti-Il-31r Subunit Beta antibodyAnti-Il-31r-Beta antibodyAnti-Il-31rb antibodyAnti-OSMR antibodyAnti-OSMRB antibody |
Information sourced from Uniprot.org