Anti-OSGEP antibody (STJA0008010)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human OSGEP
General Information
| Short Description | Rabbit polyclonal anti-tRNA N6-adenosine threonylcarbamoyltransferaseA synthaseA37 threonylcarbamoyladenosine biosynthesis protein OSGEP for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reag |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OSGEP |
| Gene ID | 55644 |
| Uniprot ID | OSGEP_HUMAN |
| Immunogen | Synthesized peptide derived from human OSGEP |
| Specificity | This antibody detects endogenous levels of OSGEP at Human, Mouse, Rat |
Additional Info
| Function | Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. |
| Protein Name | Trna N6-Adenosine ThreonylcarbamoyltransferaseN6-L-Threonylcarbamoyladenine SynthaseT(6a SynthaseO-Sialoglycoprotein EndopeptidaseHosgepT(6a37 Threonylcarbamoyladenosine Biosynthesis Protein OsgepTrna Threonylcarbamoyladenosine Biosynthesis Protein Osgep |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Trna N6-Adenosine Threonylcarbamoyltransferase antibodyAnti-N6-L-Threonylcarbamoyladenine Synthase antibodyAnti-T(6a Synthase antibodyAnti-O-Sialoglycoprotein Endopeptidase antibodyAnti-Hosgep antibodyAnti-T(6a37 Threonylcarbamoyladenosine Biosynthesis Protein Osgep antibodyAnti-Trna Threonylcarbamoyladenosine Biosynthesis Protein Osgep antibodyAnti-OSGEP antibodyAnti-GCPL1 antibody |
Information sourced from Uniprot.org