| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC/IF/FC |
| Reactivity: |
Human/Mouse/Rat/Dog |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-ORP5 (N-Term) is suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.2-0.6µg/mlIHC-5µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
OSBPL5 |
| Gene ID: |
114879 |
| Uniprot ID: |
OSBL5_HUMAN |
| Immunogen Region: |
N-Term |
| Accession Number: |
NP_065947.1; NP_663613.1; NP_001137535.1 |
| Specificity: |
This antibody is expected to recognise both reported isoforms. Variants (NP_663613.1; NP_001137535.1) encode the same isoform. |
| Immunogen Sequence: |
KEEAFLRRRFSLC |
| Function | Lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane: specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds phosphatidylserine and PI4P in a mutually exclusive manner. May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes. Binds 25-hydroxycholesterol and cholesterol. |
| Protein Name | Oxysterol-Binding Protein-Related Protein 5Orp-5Osbp-Related Protein 5Oxysterol-Binding Protein Homolog 1 |
| Database Links | Reactome: R-HSA-1482801 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLocalizes To Endoplasmic Reticulum-Plasma Membrane Contact Sites (Epcs)Localizes To The Cortical Endoplasmic Reticulum At The Epcs |
| Alternative Antibody Names | Anti-Oxysterol-Binding Protein-Related Protein 5 antibodyAnti-Orp-5 antibodyAnti-Osbp-Related Protein 5 antibodyAnti-Oxysterol-Binding Protein Homolog 1 antibodyAnti-OSBPL5 antibodyAnti-KIAA1534 antibodyAnti-OBPH1 antibodyAnti-ORP5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
