Anti-OGN antibody (20-298) (STJ28762)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal OGN (20-298) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000IHC-P:1:100-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OGN |
| Gene ID | 4969 |
| Uniprot ID | MIME_HUMAN |
| Immunogen Region | 20-298 |
| Immunogen Sequence | APPTQQDSRIIYDYGTDNFE ESIFSQDYEDKYLDGKNIKE KETVIIPNEKSLQLQKDEAI TPLPPKKENDEMPTCLLCVC LSGSVYCEEVDIDAVPPLPK ESAYLYARFNKIKKLTAKDF ADIPNLRRLDFTGNLIEDIE DGTFSKLSLLEELSLAENQL LKLPVLPPKLTLFNAKYNKI KSRGIKANAFKKLNNLTFLY LDHNALESVPLNLPESLRVI HLQFNNIASITDDTFCKAN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 20-298 of human Osteoglycin (OGN) (NP_054776.1). |
Additional Info
| Tissue Specificity | Bone. |
| Post Translational Modifications | O-glycosylated with a core 1 or possibly core 8 glycan. Contains keratan sulfate. |
| Function | Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2. |
| Protein Name | MimecanOsteoglycinOsteoinductive FactorOif |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-2022857Reactome: R-HSA-3656225Reactome: R-HSA-3656243Reactome: R-HSA-3656244 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Mimecan antibodyAnti-Osteoglycin antibodyAnti-Osteoinductive Factor antibodyAnti-Oif antibodyAnti-OGN antibodyAnti-OIF antibodyAnti-SLRR3A antibody |
Information sourced from Uniprot.org