Anti-OGG1 antibody [R08-2F5] (STJA0036494)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human OGG1
General Information
| Short Description | Rabbit monoclonal anti-OGG1 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-2F5 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | OGG1 |
| Gene ID | 4968 |
| Uniprot ID | OGG1_HUMAN |
| Immunogen | A synthesized peptide derived from human OGG1 |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. |
| Protein Name | N-Glycosylase/Dna Lyase Includes - 8-Oxoguanine Dna Glycosylase - Dna-(Apurinic Or Apyrimidinic Site LyaseAp Lyase |
| Database Links | Reactome: R-HSA-110328Reactome: R-HSA-110329Reactome: R-HSA-110330Reactome: R-HSA-110331Reactome: R-HSA-110357Reactome: R-HSA-5649702Reactome: R-HSA-9656255Reactome: R-HSA-9656256Reactome: R-HSA-9657050 O15527-4 |
| Cellular Localisation | NucleusNucleoplasmNucleus SpeckleNucleus MatrixTogether With Apex1 Is Recruited To Nuclear Speckles In Uva-Irradiated CellsIsoform 1a: NucleusIsoform 2a: Mitochondrion |
| Alternative Antibody Names | Anti-N-Glycosylase/Dna Lyase Includes - 8-Oxoguanine Dna Glycosylase - Dna-(Apurinic Or Apyrimidinic Site Lyase antibodyAnti-Ap Lyase antibodyAnti-OGG1 antibodyAnti-MMH antibodyAnti-MUTM antibodyAnti-OGH1 antibody |
Information sourced from Uniprot.org