Anti-OGDHL antibody (C-Term) (STJA0010362)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C-ternal OGDHL
General Information
| Short Description | Rabbit polyclonal anti-2-oxoglutarate dehydrogenase-like, mitochondrial (C-Term) for use in IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OGDHL |
| Gene ID | 55753 |
| Uniprot ID | OGDHL_HUMAN |
| Immunogen | Synthesized peptide derived from human C-ternal OGDHL |
| Immunogen Region | C-Term |
| Specificity | This antibody detects endogenous levels of OGDHL at Human |
Additional Info
| Function | 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis. |
| Protein Name | 2-Oxoglutarate Dehydrogenase-Like - Mitochondrial2-Oxoglutarate Dehydrogenase Complex Component E1-LikeOgdc-E1-LikeAlpha-Ketoglutarate Dehydrogenase-Like |
| Database Links | |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-2-Oxoglutarate Dehydrogenase-Like - Mitochondrial antibodyAnti-2-Oxoglutarate Dehydrogenase Complex Component E1-Like antibodyAnti-Ogdc-E1-Like antibodyAnti-Alpha-Ketoglutarate Dehydrogenase-Like antibodyAnti-OGDHL antibodyAnti-KIAA1290 antibody |
Information sourced from Uniprot.org