Immunohistochemistry analysis of OGDHL in paraffin-embedded mouse heart using OGDHL Rabbit polyclonal antibody (STJ117670) at dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-OGDHL antibody (1-110) (STJ117670)

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STJ117670
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: OGDHL
Gene ID: 55753
Uniprot ID: OGDHL_HUMAN
Immunogen Region: 1-110
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human OGDHL (NP_060715.2).
Immunogen Sequence: MSQLRLLPSRLGVQAARLLA AHDVPVFGWRSRSSGPPATF PSSKGGGGSSYMEEMYFAWL ENPQSVHKSWDSFFREASEE AFSGSAQPRPPSVVHESRSA VSSRTKTSKL
Tissue Specificity Expressed in the brain and the liver.
Function 2-oxoglutarate dehydrogenase (E1-like) component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDHC) which mediates the decarboxylation of alpha-ketoglutarate in the tricarboxylic acid cycle. The OGDHC complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) while reducing NAD(+) to NADH. The OGDHC complex is mainly active in the mitochondrion. Involved in the inhibition of cell proliferation and in apoptosis.
Protein Name 2-Oxoglutarate Dehydrogenase-Like - Mitochondrial
2-Oxoglutarate Dehydrogenase Complex Component E1-Like
Ogdc-E1-Like
Alpha-Ketoglutarate Dehydrogenase-Like
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-2-Oxoglutarate Dehydrogenase-Like - Mitochondrial antibody
Anti-2-Oxoglutarate Dehydrogenase Complex Component E1-Like antibody
Anti-Ogdc-E1-Like antibody
Anti-Alpha-Ketoglutarate Dehydrogenase-Like antibody
Anti-OGDHL antibody
Anti-KIAA1290 antibody

Information sourced from Uniprot.org

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