Anti-SEPT9 antibody (1-110) (STJ111369)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal SEPT9 (1-110) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SEPTIN9 |
| Gene ID | 10801 |
| Uniprot ID | SEPT9_HUMAN |
| Immunogen Region | 1-110 |
| Immunogen Sequence | MEPPASKVPEVPTAPATDAA PKRVEIQMPKPAEAPTAPSP AQTLENSEPAPVSQLQSRLE PKPQPPVAEATPRSQEATEA APSCVGDMADTPRDAGLKQA PASRNEKAPV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human Septin 9 (NP_001106964.1). |
Additional Info
| Tissue Specificity | Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues. |
| Function | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. |
| Protein Name | Septin-9Mll Septin-Like Fusion Protein Msf-AMll Septin-Like Fusion ProteinOvarian/Breast SeptinOv/Br SeptinSeptin D1 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonIn An Epithelial Cell LineConcentrates At Cell-Cell Contact AreasAfter Tgf-Beta1 Treatment And Induction Of Epithelial To Mesenchymal TransitionColocalizes Partly With Actin Stress FibersDuring Bacterial InfectionDisplays A Collar Shape Structure Next To Actin At The Pole Of Invading Bacteria |
| Alternative Antibody Names | Anti-Septin-9 antibodyAnti-Mll Septin-Like Fusion Protein Msf-A antibodyAnti-Mll Septin-Like Fusion Protein antibodyAnti-Ovarian/Breast Septin antibodyAnti-Ov/Br Septin antibodyAnti-Septin D1 antibodyAnti-SEPTIN9 antibodyAnti-KIAA0991 antibodyAnti-MSF antibodyAnti-SEPT9 antibody |
Information sourced from Uniprot.org