Anti-ODF2 antibody (490-540) (STJA0006504)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ODFP2 AA range: 490-540
General Information
| Short Description | Rabbit polyclonal anti-Outer dense fiber protein 2 (490-540) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ODF2 |
| Gene ID | 4957 |
| Uniprot ID | ODFP2_HUMAN |
| Immunogen | Synthesized peptide derived from human ODFP2 AA range: 490-540 |
| Immunogen Region | 490-540 |
| Specificity | This antibody detects endogenous levels of human ODFP2 |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated. Phosphorylated by TSSK4 on Ser-95. |
| Function | Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly. |
| Protein Name | Outer Dense Fiber Protein 2CenexinOuter Dense Fiber Of Sperm Tails Protein 2 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCell ProjectionCiliumCentrioleSpindle PoleFlagellumLocalized At The Microtubule Organizing Centers In Interphase And Spindle Poles In MitosisLocalized At The Distal/Subdistal Appendages Of Mother Centrioles |
| Alternative Antibody Names | Anti-Outer Dense Fiber Protein 2 antibodyAnti-Cenexin antibodyAnti-Outer Dense Fiber Of Sperm Tails Protein 2 antibodyAnti-ODF2 antibody |
Information sourced from Uniprot.org