| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ORC ubiquitin ligase 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OBI1 |
| Gene ID: |
79596 |
| Uniprot ID: |
OBI1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of RNF219 at Human |
| Immunogen: |
Synthesized peptide derived from human RNF219 |
| Function | E3 ubiquitin ligase essential for DNA replication origin activation during S phase. Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase. |
| Protein Name | Orc Ubiquitin Ligase 1Obi1Ring Finger Protein 219 |
| Cellular Localisation | ChromosomeAssociation To Chromatin Is Cell Cycle-RegulatedAbsent From Mitotic ChromosomesIs Associated With Chromatin From G1 And Partially Released From Chromatin From Mid S-Phase |
| Alternative Antibody Names | Anti-Orc Ubiquitin Ligase 1 antibodyAnti-Obi1 antibodyAnti-Ring Finger Protein 219 antibodyAnti-OBI1 antibodyAnti-C13orf7 antibodyAnti-RNF219 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
