Anti-NUCB1 antibody (302-461 aa) (STJ11106829)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NUCB1 (302-461 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:2000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUCB1 |
| Gene ID | 4924 |
| Uniprot ID | NUCB1_HUMAN |
| Immunogen Region | 302-461 aa |
| Immunogen Sequence | KNVDTNQDRLVTLEEFLAST QRKEFGDTGEGWETVEMHPA YTEEELRRFEEELAAREAEL NAKAQRLSQETEALGRSQGR LEAQKRELQQAVLHMEQRKQ QQQQQQGHKAPAAHPEGQLK FHPDTDDVPVPAPAGDQKEV DTSEKKLLERLPEVEVPQHL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 302-461 of human NUCB1 (NP_006175.2). |
Additional Info
| Tissue Specificity | Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas. |
| Post Translational Modifications | O-glycosylated. |
| Function | Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins). |
| Protein Name | Nucleobindin-1Calnuc |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembranePeripheral Membrane ProteinLumenal SideCytoplasmSecretedA Small Fraction Of The Protein May Be Cytoplasmic |
| Alternative Antibody Names | Anti-Nucleobindin-1 antibodyAnti-Calnuc antibodyAnti-NUCB1 antibodyAnti-NUC antibody |
Information sourced from Uniprot.org