| Short Description : | Rabbit polyclonal anti-NEDD8 ultimate buster 1 (566-615) for use in WB, IHC, IF and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NUB1 |
| Gene ID: | 51667 |
| Uniprot ID: | NUB1_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NYREN18. AA range:566-615 |
| Immunogen Region: | 566-615 |
| Specificity: | NUB1 Polyclonal Antibody detects endogenous levels of NUB1 protein. |
| Tissue Specificity | Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2. |
| Function | Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. |
| Protein Name | Nedd8 Ultimate Buster 1Negative Regulator Of Ubiquitin-Like Proteins 1Renal Carcinoma Antigen Ny-Ren-18 |
| Database Links | Reactome: R-HSA-8951664 |
| Cellular Localisation | NucleusPredominantly Nuclear |
| Alternative Antibody Names | Anti-Nedd8 Ultimate Buster 1 antibodyAnti-Negative Regulator Of Ubiquitin-Like Proteins 1 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-18 antibodyAnti-NUB1 antibodyAnti-NYREN18 antibody |
Information sourced from Uniprot.org
