Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Monkey |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NEDD8 ultimate buster 1 (566-615) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NUB1 |
Gene ID: |
51667 |
Uniprot ID: |
NUB1_HUMAN |
Immunogen Region: |
566-615 |
Specificity: |
NUB1 Polyclonal Antibody detects endogenous levels of NUB1 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human NYREN18. AA range:566-615 |
Tissue Specificity | Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2. |
Function | Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. |
Protein Name | Nedd8 Ultimate Buster 1Negative Regulator Of Ubiquitin-Like Proteins 1Renal Carcinoma Antigen Ny-Ren-18 |
Database Links | Reactome: R-HSA-8951664 |
Cellular Localisation | NucleusPredominantly Nuclear |
Alternative Antibody Names | Anti-Nedd8 Ultimate Buster 1 antibodyAnti-Negative Regulator Of Ubiquitin-Like Proteins 1 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-18 antibodyAnti-NUB1 antibodyAnti-NYREN18 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance